About Sangui Bio

Deep proteomics from a single drop of blood

Sangui Bio develops blood-based proteomic diagnostics that detect disease biomarkers from a fingerprick sample collected at home. Founded in 2015, the company operates from the Kolling Institute at Royal North Shore Hospital in Sydney.

Researcher working in a proteomics laboratory
Our Mission

Reading protein signatures that conventional blood tests miss

Sangui Bio was founded to commercialise discoveries that changed the way blood is analysed for disease biomarkers. Our work established that dried whole blood contains deep proteomic information that conventional plasma analysis discards.

From this foundation, the company built VeriPro, a whole-blood proteomics platform that quantifies approximately 4,000 proteins from a single 30 µL fingerprick sample. The first application is ColoPro, a blood test for early detection of colorectal cancer.

2015
Founded at the Kolling Institute, Sydney
~4,000
Proteins quantified from a single dried blood spot
30 µL
Sample volume. At-home fingerprick, no clinic visit
10+
Peer-reviewed publications (2018–2026)
The VeriPro Platform

From a fingerprick to a complex proteomic readout

VeriPro combines at-home patient-centric microsampling with LC-MS/MS mass spectrometry and machine learning. proprietary sequential extraction enables the detection and quantification of approximately 4,000 proteins from a single 30 µL dried blood spot.

The platform also supports PCR quantification of circulating tumour DNA (ctDNA) mutants such as EGFR and KRAS from the same samples, enabling multi-analyte analysis from one collection event.

Explore ColoPro
Top protein correlation results from the VeriPro platform
Clinical Home

Embedded in a world-class research network

Sangui Bio is based at the Kolling Institute, a partnership between the Northern Sydney Local Health District and the University of Sydney. Located at Royal North Shore Hospital, the company has direct access to clinical trial capacity, a network of clinicians and researchers, and world-class research infrastructure.

Our Clinical Network
Capabilities

Our expertise

Exploratory proteomics

Discovery-mode mass spectrometry covering thousands of proteins per sample, optimised for the unique chemistry of dried whole blood.

Vascular and microsample fractionation

Proprietary sequential extraction methods that separate intracellular, membrane and cytokine fractions from a single dried blood spot.

Integrated clinical network

Embedded in the Northern Sydney Local Health District tertiary network, with established ethics and regulatory infrastructure.

Mass spectrometry

DIA mass spectrometry quantifying ~4,000 proteins from 30 µL of dried blood, well beyond the reach of conventional plasma analysis.

Modular longitudinal analysis

At-home patient-centric microsampling that supports repeat testing across surveillance windows and clinical trials.

Cost-effective scalable technologies

A platform built for population-scale deployment: postable sample collection, automated extraction, and centralised LDT processing.

Partner with us

We work with clinicians,
researchers, and industry.

Sangui Bio collaborates with gastroenterology practices, clinical research groups, and strategic partners. If you are interested in our work, we would like to hear from you.

Contact Sangui Bio