Sangui Bio's clinical development is guided by independent expert counsel and grounded in an embedded position within a tertiary research network in Sydney.
Sangui Bio is establishing a Clinical and Scientific Advisory Board, bringing together leaders in gastroenterology, cancer prevention, and diagnostics to guide the clinical development and validation of its whole-blood proteomic platform. Board members provide independent scientific and clinical counsel as Sangui Bio advances the VeriPro platform and ColoPro pre-cancerous lesion assay toward clinical and commercial use.
Dr Ladabaum is Professor of Medicine (Gastroenterology and Hepatology) and Director of the Gastrointestinal Cancer Prevention Program at Stanford University School of Medicine. He is an internationally recognised authority on colorectal cancer screening, with particular expertise in the comparative effectiveness, economic impact, and cost-effectiveness of screening and surveillance strategies. His research spans epidemiological studies, observational and interventional clinical trials, decision-analytic modelling, and systematic reviews.
As inaugural member of Sangui Bio's Clinical and Scientific Advisory Board, Professor Ladabaum advises on the clinical positioning and evidence strategy for ColoPro, the company's blood-based test for colorectal neoplasia, with a focus on its role in post-polypectomy surveillance and the broader colorectal screening pathway.
“Non-invasive surveillance and screening of the colon and rectum that achieves high detection rates for advanced precancerous polyps would revolutionize clinical practice, especially if it is with a convenient, accessible, at-home method for collecting a stable, small blood sample that can then be mailed to a laboratory.”
The Kolling Institute is the longest-running medical research institute in New South Wales, holding a key role in research activities for over 100 years. It is jointly managed by the Northern Sydney Local Health District and the University of Sydney.
Within the NSLHD, the main precinct comprises Royal North Shore Hospital, a major public hospital, alongside the North Shore Private Hospital and the North Shore Health Hub, which houses major private healthcare providers such as Ramsay Health and GenesisCare.
Sangui Bio benefits from being part of this high-volume tertiary clinical network. Access to quality research facilities, an efficient ethics and regulatory infrastructure, low resource burden for companies, and rapid regulatory approvals together provide a distinctive advantage for clinical biomarker development.